100% Pure Distilled Water, Vegan Food Grade High Molecular Weight Hyaluronic Acid (MW 900KDA min.), Organic Plant Extract (Natural Preservative).

Hyaluronic Acid (HA) is a natural substance vital to our bodies. Its molecular size dictates its many health benefits, including reducing inflammation, supporting cell health, stimulating Type II collagen, and providing the unique lubricating properties of synovial fluid.

It works by interacting with various receptors and pathways, playing a key role in tempering inflammation and promoting cellular well-being. Unlike its smaller counterparts, HMW-HA generally avoids activating pro-inflammatory pathways like Toll-like receptor 4 (TLR4). Instead, it can help suppress inflammatory signals by promoting anti-inflammatory responses and influencing factors like SOCS3 (Suppressor of Cytokine Signaling 3), which helps regulate immune responses and limit excessive inflammation. This molecular interplay supports cellular health and stimulates beneficial processes like Type II collagen production, essential for maintaining healthy tissues.

High Molecular Weight Hyaluronic Acid (HMW-HA) The larger molecular size is critical to its profound health benefits. Beyond its well-known role in joint lubrication and shock absorption (the "magical non-Newtonian properties" of synovial fluid), HMW-HA actively modulates cellular responses. The larger molecules are carried out of the large intestine through mucus membrane transfer and reach their final destination, your joints. Without this larger MW our bodies would absorb the HA in our small intestines never reaching critical joints in the body.

1. Take 20ml-40ml per day on an empty stomach

2. 20ml=300mg of HMWHA

We are committed to complete transparency, purity and quality. If you have any questions not answered on our site please email us at info@highmolecular.com

Allergic reactions, mild skin irritation and or digestive discomfort may occur at very high doses.

Serum HA levels in Synovial fluid range from 1-4 mg/mL. It is important to note that the concentration and molecular weight of HA can decrease with age. In conditions like osteoarthritis, where the fluid's viscosity and elasticity are reduced, studies have shown that when properly doesed, oral supplementation continues to be effective at reducing pain syptoms in test subjects.

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